書誌事項
- タイトル別名
-
- Cardiotonic effects of proscillaridin A
- Proscillaridin A ノ キョウシン サヨウ ニ ツイテ
この論文をさがす
抄録
Cardiotonic effect of proscillaridin A, cardiac glycoside derived from a squill, was tested in some methods.<br> 1. Lethal doses (Hatcher doses) of proscillaridin A were 0.142mg/kg in cats, 0.152mg/kg in dogs, and 0.484mg/kg in rabbits, whereas the dose of g-strophanthin was 0.104mg/kg in cats.<br> 2. 3.16×10-8 Molar concentration of proscillaridin A showed a persistent 60% increase of contractile force in cat papillary muscle preparation.<br> 3. Contractile force of left ventricular muscle showed 9% increase after the second administration (total proscillaridin A 0.04mg/kg) in phenobarbital induced myocardial depression.<br> 4. The ratio between the maximum rate of development isometric tension (dp/dt) and a constant fraction of the integrated isometric tension developed (IIT) showed 12% increase after the second administration of proscillaridin A.
収録刊行物
-
- 日本薬理学雑誌
-
日本薬理学雑誌 69 (1), 31-39, 1973
公益社団法人 日本薬理学会
- Tweet
キーワード
詳細情報 詳細情報について
-
- CRID
- 1390001204275685376
-
- NII論文ID
- 130000757810
- 10005527133
-
- NII書誌ID
- AN00198335
-
- COI
- 1:CAS:528:DyaE2MXotVCqtw%3D%3D
-
- ISSN
- 13478397
- 00155691
-
- NDL書誌ID
- 7624872
-
- PubMed
- 4737525
-
- 本文言語コード
- ja
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可