Electrocardiographic changes in rats after inhalation of dichlorotetrafluoroethane,Arcton 114,C2C12F4

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  • DURAKOVIC Zijad
    Department of Internal Medicine, University Hospital Rebro Institute for Medical Research and Occupational Health, Yugoslav Academy of Science and Arts
  • STILINOVIC Luka
    Department of Internal Medicine, University Hospital Rebro Institute for Medical Research and Occupational Health, Yugoslav Academy of Science and Arts
  • BAKRAN Ivan
    Department of Internal Medicine, University Hospital Rebro Institute for Medical Research and Occupational Health, Yugoslav Academy of Science and Arts

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  • Electrocardiographic Changes in Rats after Inhalation of Dichlorotetrafluoroethane, Arcton 114, C<sub>2</sub>Cl<sub>2</sub>F<sub>4</sub>
  • Electrocardiographic changes in rats af

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The effects of dichlorotetrafluoroethane, Arcton 114, on the heart of rats were examined in 17 white rats. The animals inhaled diehlorotetrafluoroethane for I or 1.5 min. Severe electrocardiographic changes including marked bradycardia, atrioventricular heart block of the second degree and complete heart block were registered. Cardiac standstill appearing 11 to 31 min after inhalation was a death cause in all rats. These results are similar to our previous results concerning the effects of dichlorodifluoromethane (Arcton 12) on the heart of rats.

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