Relationship between Catecholamine and Renin-Angiotensin System in Spontaneously Hypertensive Rats
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- KAJIWARA Nagao
- Second Department of Internal Medicine, Nihon University School of Medicine and Department of Cardiology, Surugadai Nihon University Hospital
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- KOBAYASHI Yoshiko
- Second Department of Internal Medicine, Nihon University School of Medicine and Department of Cardiology, Surugadai Nihon University Hospital
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- HASHIDA Jun
- Second Department of Internal Medicine, Nihon University School of Medicine and Department of Cardiology, Surugadai Nihon University Hospital
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- UCHIYAMA Takahisa
- Second Department of Internal Medicine, Nihon University School of Medicine and Department of Cardiology, Surugadai Nihon University Hospital
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- KITA Takashi
- Second Department of Internal Medicine, Nihon University School of Medicine and Department of Cardiology, Surugadai Nihon University Hospital
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- SATOH Masahiko
- Second Department of Internal Medicine, Nihon University School of Medicine and Department of Cardiology, Surugadai Nihon University Hospital
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- ONO Masashi
- Second Department of Internal Medicine, Nihon University School of Medicine and Department of Cardiology, Surugadai Nihon University Hospital
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- IZEKI Yasuo
- Second Department of Internal Medicine, Nihon University School of Medicine and Department of Cardiology, Surugadai Nihon University Hospital
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- TEI Tateo
- Second Department of Internal Medicine, Nihon University School of Medicine and Department of Cardiology, Surugadai Nihon University Hospital
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- TERASHIMA Hiroshi
- Second Department of Internal Medicine, Nihon University School of Medicine and Department of Cardiology, Surugadai Nihon University Hospital
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- MISHINA Nobuaki
- Second Department of Internal Medicine, Nihon University School of Medicine and Department of Cardiology, Surugadai Nihon University Hospital
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- KUSHIRO Toshio
- Second Department of Internal Medicine, Nihon University School of Medicine and Department of Cardiology, Surugadai Nihon University Hospital
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- HATANO Michinobu
- Second Department of Internal Medicine, Nihon University School of Medicine and Department of Cardiology, Surugadai Nihon University Hospital
Abstract
PRA and BP were measured after administration of NE and FA to evaluate the relationship between plasma NE and renin-angiotensin system in SHR.<br>(1) PRA increased after drip infusion of NE.<br>(2) BP decreased in proportion to the dose of FA administered and this effect was more prominent in the group with higher blood pressure before administration.<br>(3) PRA increased after intraperitoneal administration of FA, whose vasodilating effect could play a role as a renin releasing factor. During oral administration, BP decreased but PRA showed no change, and this discrepancy could be due to the time needed to achieve proper BP and its final level.
Journal
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- Japanese Heart Journal
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Japanese Heart Journal 17 (3), 410-411, 1976
International Heart Journal Association
