A Clinical Study of the Effect of Coenzyme Q on Congestive Heart Failure
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- ISHIYAMA Taro
- Third Department of Internal Medicine, Osaka University Medical School
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- MORITA Yoshiharu
- Third Department of Internal Medicine, Osaka University Medical School
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- TOYAMA Seiichi
- The Center for Adult Diseases
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- YAMAGAMI Toru
- The Center for Adult Diseases
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- TSUKAMOTO Nozomu
- Department of Internal Medicine, Nishinomiya City Central Hospital
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- WADA Noboru
- Kobe Shosei Hospital
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- OHKUBO Masaaki
- Kobe Shosei Hospital
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- YAMAMURA Yuichi
- Third Department of Internal Medicine, Osaka University Medical School
書誌事項
- タイトル別名
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- clinical study of the effect of coenzym
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抄録
Expecting activation of myocardial energy liberation, coenzyme Q was applied as a treatment to 55 patients suffering from congestive heart failure. Daily doses of 50 to 100mg of coenzyme Q7 were injected intravenously in 21 cases for 3 to 35 days. Daily doses of 60mg of coenzyme Q7 were administered perorally in 17 cases for 14 to 196 days. Daily doses of 30mg of coenzyme Q10 were administered perorally in 17 cases for 7 to 182 days. Clinical effects were evaluated within 4 weeks by the criteria using a scoring method of severity of congestive heart failure which was devised by the authors. In summary a certain effect was found in 20 cases and a mild effect was observed in 29 cases. No significant changes were observed in heart rate and blood pressure. Exanthema appeared in 2 patients of the group of coenzyme Q7 intravenous injection. In conclusion the therapeutic effect of coenzyme Q was thought to be mild but stable in supplement to digitalis therapy in cases of congestive heart failure.
収録刊行物
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- Japanese Heart Journal
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Japanese Heart Journal 17 (1), 32-42, 1976
International Heart Journal刊行会
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詳細情報 詳細情報について
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- CRID
- 1390282680017308160
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- NII論文ID
- 130000763376
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- NII書誌ID
- AA00690786
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- ISSN
- 1348673X
- 00214868
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- NDL書誌ID
- 1690012
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- PubMed
- 778433
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可