Changes in Catecholaminergic Neurons in Medulla Oblongata of Spontaneously Hypertensive rat

  • Ohtsuji M.
    Department of Physiology, School of Medicine, Fujita Gakuen University
  • Nomura M.
    Department of Physiology, School of Medicine, Fujita Gakuen University

抄録

We determined catecholamine (CA) content in brain of spontaneously hypertensive rat (SHR) and observed a decrease of noradrenarine (NA) content in the brain stem as previous report. Then we used Glutaraldehyde-formaldehyde fluorescence method for histochemical study. Fluorescence of ventral Al and dorsal A2 cell bodies in medulla oblongata was decreased. NA accumulation in caudal nervous ending of nucleus tractus solitarius (NTS) was reduced in SHR of pre-hypertensive stage aged 4 weeks. There were no changes in other regions, thalamus, hypothalamus, substantia nigra, locus ceruleus and periventricular nucleus.

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