Pulmonary Alveolar Proteinosis Successfully Treated with Ambroxol.

• HASHIZUME Toshihiko

  The Department of Internal Medicine, Yokohama Sakaekyosai Hospital

抄録

A 79-year-old woman was admitted to hospital due to a four-month history of a cough and dyspnea on exertion. Chest CT scans revealed ground glass opacity with thickened interlobular septa in both lungs. Bronchoalveolar lavage fluid (BALF) had milky appearance and revealed large acellular eosinophilic amorphous bodies positively stained with periodic acid-Schiff (PAS). Autoantibodies against granulocyte-macrophage colony-stimulating factor (GM-CSF) were present in sera and BALF from the patient. Ambroxol was started in a daily dose of 45 mg orally. Her oxygen saturation improved and abnormal shadows in CT scan disappeared 6 months after beginning the therapy.<br>(Internal Medicine 41: 1175-1178, 2002)

収録刊行物

• Internal Medicine

  Internal Medicine 41 (12), 1175-1178, 2002

  一般社団法人 日本内科学会

キーワード

• bronchoalveolar lavage
• granulocyte-macrophage colony-stimulating factor (GM-CSF)

詳細情報

• CRID: 1390001204867831296
• NII論文ID: 130000767277
• NII書誌ID: AA10827774
• DOI: 10.2169/internalmedicine.41.1175
• COI: 1:STN:280:DC%2BD3s%2FhsVOlsw%3D%3D
• ISSN: 13497235
• ISSN: 09182918
• NDL書誌ID: 6400290
• PubMed: 12521210
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I6400290
• Web Site: http://www.jstage.jst.go.jp/article/internalmedicine1992/41/12/41_12_1175/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2003147952
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可