Hodgkin's Disease Preceded by Unique Neurological Symptoms.

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This is the first case report of Hodgkin's disease (HD) which showed both remission and exacerbation of neurological signs before a confirmed diagnosis of HD. The episodes occurred three times and multiple lesions were involved. Immunoabsorption plasmapheresis and double filtration plasmapheresis were effective for the first episode, whereas, corticosteroids partly improved the second and third episodes. Fever and lymph node swelling were apparent afterward and she was diagnosed as having HD from a supraclavicular lymph node biopsy. The remaining neurologic deficits responded to chemotherapy and radiotherapy. The neurological symptoms were considered as a paraneoplastic syndrome of HD.<br>(Internal Medicine 40: 819-821, 2001)

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  • Internal Medicine

    Internal Medicine 40 (8), 819-821, 2001

    一般社団法人 日本内科学会

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