IGF-II Producing Hepatic Fibrosarcoma Associated with Hypoglycemia.
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- KOTANI Ko
- the Second Department of Internal Medicine, Kobe University
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- TSUN Motomu
- the Department of Pathology, Itami City Hospital
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- OKI Atsushi
- the Department of Internal Medicine, Itami City Hospital
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- KASHIHARA Takeshi
- the Department of Internal Medicine, Itami City Hospital
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- YAMADA Katsumi
- the Department of Surgery, Itami City Hospital
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- KAWAKAMI Fusao
- the Department of Internal Medicine, Itami City Hospital
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- TAKO Hajime
- the Department of Internal Medicine, Itami City Hospital
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- OKUNO Giichi
- the Department of Internal Medicine, Itami City Hospital
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- HIZUKA Naomi
- the Second Department of Internal Medicine, Tokyo Women's Medical College
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- AIBA Motohiko
- the Department of Surgical Pathology, Tokyo Women's Medical College
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- KASUGA Masato
- the Second Department of Internal Medicine, Kobe University
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Abstract
A 67-year-old male was admitted with the complaint of weakness at hunger early in the morning, when blood glucose was less than 40 mg/dl. The abdominal ultrasonogram and computerized tomogram demonstrated a huge tumor in the right liver lobe. Hypoglycemia disappeared after transcatheter arterial embolization. Then hepatic lobectomy was performed. The tumor was histologically shown to be a fibrosarcoma. Insulin-like growth factor-II was intensely stained in the Golgi area of the tumor cells, suggesting its role in the mechanism of hypoglycemia.<br>(Internal Medicine 32: 897-901, 1993)
Journal
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- Internal Medicine
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Internal Medicine 32 (12), 897-901, 1993
The Japanese Society of Internal Medicine