IGF-II Producing Hepatic Fibrosarcoma Associated with Hypoglycemia.

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Abstract

A 67-year-old male was admitted with the complaint of weakness at hunger early in the morning, when blood glucose was less than 40 mg/dl. The abdominal ultrasonogram and computerized tomogram demonstrated a huge tumor in the right liver lobe. Hypoglycemia disappeared after transcatheter arterial embolization. Then hepatic lobectomy was performed. The tumor was histologically shown to be a fibrosarcoma. Insulin-like growth factor-II was intensely stained in the Golgi area of the tumor cells, suggesting its role in the mechanism of hypoglycemia.<br>(Internal Medicine 32: 897-901, 1993)

Journal

  • Internal Medicine

    Internal Medicine 32 (12), 897-901, 1993

    The Japanese Society of Internal Medicine

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