Immunological Stuides on Opportunistic Infection and the Development of Adult T-cell Leukemia.

  • TASHIRO Takayoshi
    the Second Department of Internal Medicine, Oita Medical University
  • YAMASAKI Tohru
    the Second Department of Internal Medicine, Oita Medical University
  • NAGAI Hiroyuki
    the Second Department of Internal Medicine, Oita Medical University
  • KIKUCHI Hiroshi
    the Second Department of Internal Medicine, Oita Medical University
  • NASU Masaru
    the Second Department of Internal Medicine, Oita Medical University

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Three patients with opportunistic infection preceding adult T-cell leukemia (ATL) are presented : a 66-year-old woman with cryptococcosis and Pneumocystis carinii pneumonia, a 46-year-old man with Pneumocystis carinii pneumonia, and a 55-year-old woman with cryptococcosis. Although, at the first examination, the first two had smoldering type ATL and the third case was an HTLV-I carrier, all three developed overt ATL 14-16 months after the onset of opportunistic infection. It is considered that there is immune suppression already present in HTLV-I carriers and in patients with smoldering ATL, and opportunistic infection is predictive of the development of ATL.<br>(Internal Medicine 31 : 1132-1136, 1992)

収録刊行物

  • Internal Medicine

    Internal Medicine 31 (9), 1132-1136, 1992

    一般社団法人 日本内科学会

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