Adrenal Myelolipoma Associated with Congenital Adrenal 21-Hydroxylase Deficiency.

  • MURAKAMI Chika
    the Fourth Department of Medicine and Department of Pathology, Teikyo University School of Medicine
  • ISHIBASHI Miyuki
    the Fourth Department of Medicine and Department of Pathology, Teikyo University School of Medicine
  • KONDO Masahiro
    the Fourth Department of Medicine and Department of Pathology, Teikyo University School of Medicine
  • OHSHIRO Sumako
    the Fourth Department of Medicine and Department of Pathology, Teikyo University School of Medicine
  • FUJITA Mutsumi
    the Fourth Department of Medicine and Department of Pathology, Teikyo University School of Medicine
  • SATO Shigenobu
    the Fourth Department of Medicine and Department of Pathology, Teikyo University School of Medicine
  • KAKO Makoto
    the Fourth Department of Medicine and Department of Pathology, Teikyo University School of Medicine
  • FURUE Hisashi
    the Fourth Department of Medicine and Department of Pathology, Teikyo University School of Medicine
  • MIZUGUCHI Kunio
    the Fourth Department of Medicine and Department of Pathology, Teikyo University School of Medicine
  • YAMAJI Tohru
    the Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo

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抄録

The occurrence of adrenal myelolipomas is reported in an untreated patient with congenital adrenal 21-hydroxylase deficiency. Laparotomy demonstrated the presence of two lesions, a large tumor which arose from an ectopic adrenal cortex and a smaller tumor in the left adrenal gland. Six cases of adrenal myelolipomas and congenital adrenal hyperplasia have been reported in the literature. All patients were associated with excessive ACTH secretion for a long period of time. The relative frequency of this association, coupled with the observation by Selye and Stone (Am J Pathol 26 : 211, 1950) that anterior pituitary extracts cause myelolipomatous changes in rats, may indicate a possible role for ACTH in the development of myelolipomas.<br>(Internal Medicine 31 : 803-806, 1992)

収録刊行物

  • Internal Medicine

    Internal Medicine 31 (6), 803-806, 1992

    一般社団法人 日本内科学会

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