クリアリング法による結腸がんリンパ節転移に関する研究

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  • Studies on the Lymph Node Metastases of the Colon Cancer by the Modified Clearing Method

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The lymph node metastases of the colon cancer were studied using the modified clearing method. This method enabled not only to examine smaller nodes than the conventional one, but also toclarify the relationship among the primary site of the cancer, feeding vessels, modes of the cancer spread and positions of metastatic nodes. In 60 cases, the nodal involvements were found in 56.7%, and and the incidence of the lymph node metastasis was 4.3% of 4329 nodes examined.<BR>In the right side colon cancer, metastases to the epicolic and paracolic nodes were confined within 7 cm from the tumor margin, while in the left side colon cancer within 4 cm.<BR>In the right side colon cancer, the metastases to the intermediate nodes were found in 15.0%, and to the main nodes, 10.0%.<BR>In the left side colon cancer, the metastases to the intermediate nodes were 20.0%, and to the main nodes 12.5%.<BR>Jumping metastases were recognized in 16 out of 60 cases (29.4%). As the rate of jumping metastases is unexpectedly high, it was considered that lymph node dissection for colon cancer should be done as far as main nodes.

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