制限食下便潜血３枚法と問診の併用による大腸がん集団検診

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  • Mass screening for colorectal cancer by testing for occult blood under a restricted diet and using a questionnaire.

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Because of the recent increase in the incidence of colorectal cancer in Japan, attempts were made to find an effective method for screening asymptomatic patients with this cancer. A total of 12, 520 participants in Osaka were screened in a 2-year program from April 1982 by testing for fecal occult blood under a restricted diet, and using a medical questionnaire. Occult blood in feces was examined for 3 consecutive days using one guaiac-impregnated slide (Shionogi B) each day. This slide was about twice as sensitive as the Hemoccult slide. Further diagnostic work-ups were required in 3, 434 individuals, of which 2, 602 (75.7 %) were due to positive occult blood. Proctosigmoidoscopy was performed in 2, 214 (64.4 %) of these persons, barium enema in 1, 397 persons, and flexible colonoscopy in 187 persons. Colorectal cancers were detected in 18 patients (0.14 % of the total screened), ten of these cancers being in an early stage. Thus this screening method is reliable for detecting asymptomatic cancer of the colon and rectum.

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