Psychological Profiles and Health Status in Japanese Female Patients with Systemic Lupus Erythematosus: The Miyagi Lupus Collaborative Study.

  • Minami Yuko
    Division of Epidemiology;Miyagi Cancer Center Research Institute
  • Sasaki Takeshi
    Department of Rheumatology and Hematology,Graduate School of Medicine,Tohoku University
  • Arai Yumiko
    Research Unit for Nursing,Caring Sciences and Psychology,National Institute of Longevity Sciences
  • Hosokawa Toru
    Department of Human Development,Faculty of Education,Tohoku University
  • Hisamichi Shigeru
    Department of Public Health,Graduate School of Medicine,Tohoku University
  • Lupus Miyagi
    See acknowledgment

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  • 20010207

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Psychological factors have been suspected to be associated with the development of systemic lupus erythematosus(SLE)and patients health status.However, psychological profiles among Japanese patients with SLE have been poorly understood.We started a prospective study of female patients with SLE in 1995.Using the baseline data from 279 patients in this prospective study, we cross-sectionally analyzed the relations of clinical factors and social factors to psychological factors, and the association between psychological factors and mental and physical health status.We used the Japanese notion ikigal as an indicator of mental health, and ambulatory activity as an indicator of their physical health, respectively.To measure psychological factors, the short-form of the Eysenck Personality Questionnaire-Revised(short EPQ-R)and the Multidimensional Health Locus of Control(HLOC)scale were used.Active phase of the disease was significantly related to the neuroticism score in the short EPQ-R.Educational level was inversely related to the scores of powerful others and chance HLOC belief.As for health status, the internal HLOC belief was significantly associated with /k/gal and the chance HLOC belief was inversely associated with ambulatory activity.The scores on the short EPQ-R (Extraversion/lntroversion and Neuroticism)were exclusively related to ikigai.This study suggests that psychological factors may have effects on both the development of SLE and patients health status.JEpidemiol, 2002;12:55-63

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