めまいに対するイブジラストの治療効果 医師の評価と患者による日常生活の障害の改善から評価した治療効果の比較

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タイトル別名
  • Therapeutic Effect of Ibudilast in Dizzy Patients : Comparison of Self-assessment of Handicap in Everyday Life Due to Dizziness and Clinical Evaluation by Physicians.
  • Comparison of Self-assessment of Handicap in Everyday Life Due to Dizziness and Clinical Evaluation by Physicians
  • 医師の評価と患者による日常生活の障害の改善から評価した治療効果の比較

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The therapeutic effect of ibudilast, a cerebral vasodilator, was evaluated in 106 patients with vertigo or dizziness. The patients were given a 10 mg capsule of ibudilast 3 times a day for over 4 weeks. In 77 patients (72.6%), symptoms and/or signs were reduced. Mild side-effects were noted in 3 patients (2.8%). These results suggest that ibudilast is a clinically useful drug for the treatment of vertigo or dizziness. A questionnaire consisting of 14 questions was used to evaluate the handicaps in everyday life due to dizziness in 25 patients. A discrepancy was noted between the doctor's evaluation of improvement and the patient's selfassesment. It appeared that patients with emotional disturbances and limited social activity due to dizziness perceived greater handicaps.

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