ウコギ（Ａｃａｎｔｈｏｐａｎａｘ　ｓｉｅｂｏｌｄｉａｎｕｓ）葉投与が新生児期のストレプトゾトシン投与による２型糖尿病ラットの耐糖能に及ぼす影響

• 田渕 三保子

  山形県立米沢女子短期大学

• 田村 朝子

  山形県立米沢女子短期大学

• 山田 則子

  山形県立米沢女子短期大学

書誌事項

タイトル別名

• Effect of Ukogi (Acanthopanax sieboldianus) Leaves on Glucose Tolerance in Rats with Neonatally Induced Streptozotocin (Type 2) Diabetes
• ウコギ Acanthopanax sieboldianus ハ トウヨ ガ シンセイジキ ノ ストレプトゾトシン トウヨ ニ ヨル 2ガタ トウニョウビョウ ラット ノ タイトウノウ ニ オヨボス エイキョウ

抄録

The effect of Ukogi (Acanthopanax siebldianus) leaves on blood glucose level and glucose tolerance was investigated in rats with neonatally induced streptozotocin (type 2) diabetes (n-STZ rats). Neonatal rats were made diabetic by injection of 80mg/kg STZ. From the age of 8 weeks, n-STZ rats were given a diet containing ukogi (DM-U group) or cellulose (DM-C group), or a control diet (DM group), for 10 weeks. Normal rats were given the control diet (Normal group). Impairment of glucose tolerance in rats of the DM group increased with age. In the DM-U group, however, glucose tolerance was better than in the DM group (p<0.05). At the end of the experiments, the blood glucose level in the DM group was higher than that in the Normal group, although that in the DM-U group was significantly lower than in the DM group (p<0.05). The serum triglyceride level was also decreased by intake of ukogi leaves (p<0.05). These results suggest that ukogi leaves improve the blood glucose level, glucose tolerance and serum triglyceride in n-STZ rats.

収録刊行物

• 日本栄養・食糧学会誌

  日本栄養・食糧学会誌 56 (4), 243-246, 2003

  公益社団法人 日本栄養・食糧学会

キーワード

• ウコギ
• 新生児期のストレプトゾトシン投与による2型糖尿病
• ラット
• 血糖値
• 耐糖能

詳細情報

• CRID: 1390282681268840832
• NII論文ID: 130000856419
• NII書誌ID: AN00311992
• DOI: 10.4327/jsnfs.56.243
• ISSN: 18832849
• ISSN: 02873516
• NDL書誌ID: 6673783
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I6673783
• Web Site: https://search.jamas.or.jp/link/ui/2004038941
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可