IHNウイルスに対する単クローン抗体の作製とその性状

DOI Web Site 被引用文献2件
  • SCHULTZ C. L.
    Department of Microbiology, University of Maryland, College Park
  • LIDGERDING B. C.
    U.S. Fish and Wildlife Service, National Fish Health Research Laboratory
  • MCALLISTER P. E.
    U.S. Fish and Wildlife Service, National Fish Health Research Laboratory
  • HETRICK F. M.
    Department of Microbiology, University of Maryland, College Park

書誌事項

タイトル別名
  • Production and characterization of monoclonal antibody against infectious hematopoietic necrosis virus.
  • IHNウイルスに対する単クローン抗体の作製とその性状〔英文〕
  • IHN ウイルス ニ タイスル タン クローン コウタイ ノ サクセイ ト ソ

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抄録

A hybridoma cell line that continually secretes antibody against infectious hematopoietic necrosis virus was developed and designated M-IHNV-W1. Antibodies in culture fluids were concentrated and purified by Protein A Sepharose CL-4B affinity chromatography. The immunoglobulin was isotyped as IgG 2b with a kappa light chain. The IgG was specific for infectious hematopoietic necrosis virus and had binding activity but low neutralizing activity. Little cross-reactivity occurred with viral hemorrhagic septicemia or infectious pancreatic necrosis viruses.

収録刊行物

  • 魚病研究

    魚病研究 20 (2/3), 339-341, 1985

    日本魚病学会

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