治療中止後急性肝不全と溶血性貧血を呈して死亡したＷｉｌｓｏｎ病の１例

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  • An autopsy case of Wilson's disease complicating fatal acute liver failure and hemolytic anemia after discontinuation of therapy.

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A16-year-old girl was admitted to our hospital because of general malaise and icterus. She had been diagnosed as Wilson's disease for 5 years proved by family examination when her senior brother was diagnosed as this disease. She had been doing well without symptoms by taking D-penicillamine until self-discontinuation of the medication eight months ago. She presented progressive hepatic failure and hemolytic anemia and died on the 10th hospital day. The clinical course of this case is rare in Japan. Physicians, together with patients and the family, should recognize that discontinuation of therapy might result in fatal outcome in this disease.

収録刊行物

  • 肝臓

    肝臓 33 (8), 649-653, 1992

    一般社団法人　日本肝臓学会

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