肝細胞癌の格子線維構築特性についての病理組織学的検討ならびに画像解析法による定量的評価

DOI Web Site

書誌事項

タイトル別名
  • Histopathological and morphometric quantitative studies on the architectural changes of reticulin fibers in hepatocellular carcinomas.

この論文をさがす

抄録

In order to disclose architectural characteristics of reticulin fibers in hepatocellular carcinoma (HCC), 45 cases of HCC, 5 cases of liver cirrhosis (LC) and 10 cases of normal liver were submitted for the present study. Histological investigations were thoroughly performed on reticulin stain preparations. "Hook-shaped reticulin fiber", which has not been reported before, was described here firstly, and its morphological findings were reported. Comparing with the normal liver, the number of fibers was slightly decreased in LC, and was remarkably diminished in HCC. On the reticulin architectures, discontinuity, irregular running pattern, variable size, tapering and lump formation of reticulin fibers and occurrence of intratumor-scars were considered to be characteristic changes for HCC. It was also confirmed quantitatively that a density and amount of reticulin fibers was decreased in accordance with histological grade of differentiation of HCC.

収録刊行物

  • 肝臓

    肝臓 33 (12), 938-946, 1992

    一般社団法人　日本肝臓学会

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ