肝血行動態に基づいたDynamic CT  慢性肝疾患における肝血行動態についての検討

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タイトル別名
  • Dynamic computed tomography based on hepatic hemodynamics. A study of hepatic hemodynamics in chronic liver diseases.
  • 慢性肝疾患における肝血行動態についての検討

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Dynamic CT was performed in 14 normal subjects, 11 cases with chronic hepatitis and 43 cases with liver cirrhosis. One ml/kg of 65% meglumine amidotrizoate was injected in 10 seconds via an antecubital vein. Serial scans were undergone at 18sec. as a hepatic arterial phase, 34sec. as an early portal phase, 50sec. as a middle portal phase, 90sec. and 120sec. after the beginning of the injection, on the basis of circulation times of hepatic arterial and portal venous streams determined by 133Xe method as reported previously. Concentration of contrast medium was measured on hepatic parenchyma. The concentration values in liver cirrhosis at 34 and 50sec. were 20.9±5.7 and 27.6±5.7H.U., respectively, and each was significantly (p<0.001) lower than 44.8±5.1 and 40.8±5.5H.U. at each time in normal subject. Those values in chronic hepatitis were indicated to be median between in liver cirrhosis and in normal subjects.<BR>Therefore, it was suggested that dynamic CT based on hepatic hemodynamics was a useful method for diagnosis and evaluaton of hemodynamics in chronic liver diseases.

収録刊行物

  • 肝臓

    肝臓 27 (6), 781-788, 1986

    一般社団法人 日本肝臓学会

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