Clinical Studies of Oral Quinolone Once Daily in the Treatment of Lower Respiratory Tract Infections.
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- YANO TAKAFUMI
- Department of Medicine, Kurume University School of Medicine
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- TANAKA FUMIO
- Department of Medicine, Kurume University School of Medicine
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- OUCHI KAZUHIRO
- Department of Medicine, Kurume University School of Medicine
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- KAWAHARA MASAO
- Department of Medicine, Kurume University School of Medicine
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- FUJINO KAZUMA
- Department of Medicine, Kurume University School of Medicine
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- SHIMA RUMI
- Department of Medicine, Kurume University School of Medicine
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- RIKIMARU TORU
- Department of Medicine, Kurume University School of Medicine
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- ICHIKAWA YOICHIRO
- Department of Medicine, Kurume University School of Medicine
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- OIZUMI KOTARO
- Department of Medicine, Kurume University School of Medicine
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The efficacy and safety of oral of loxacin, 400 mg once daily, for the treatment of patients with lower respiratory tract infections were studied. The most common species recovered from the sputum specimens of these patients were Haemophilus influenzae, followed by Streptococcus pneumoniae (S.pneumoniae), Staphylococcus aureus (S. aureus), Gram positive cocci unidentified, Pseudomonas aeruginosa (P. aeruginosa), Morexella catarrhalis, Streptococcus epidermidis, and another Haemophilus species in this order. All these bacteria were susceptible to of loxacin except for one strain of methicillin resistant S. aureus. A satisfactory clinical outcome was achieved in 34 of 40 patients (85%). It is concluded that of loxacin, 400 mg once daily, is useful for patients with respiratory tract infections.
収録刊行物
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- Ｔｈｅ Ｋｕｒｕｍｅ Ｍｅｄｉｃａｌ Ｊｏｕｒｎａｌ
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Ｔｈｅ Ｋｕｒｕｍｅ Ｍｅｄｉｃａｌ Ｊｏｕｒｎａｌ 40 (4), 213-218, 1993
久留米大学医学部 The Kurume Medical Journal 編集部
