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- SUGIYAMA TORU
- Department of Obstetrics and Gynecology, Kurume University School of Medicine
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- NISHIDA TAKASHI
- Department of Obstetrics and Gynecology, Kurume University School of Medicine
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- USHIJIMA KIMIO
- Department of Obstetrics and Gynecology, Kurume University School of Medicine
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- KATABUCHI HIDEKI
- Department of Obstetrics and Gynecology, Kurume University School of Medicine
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- SHIBUE KENICHI
- Department of Obstetrics and Gynecology, Kurume University School of Medicine
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- NAKANAMI MASAMICHI
- Department of Obstetrics and Gynecology, Kurume University School of Medicine
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- YAKUSHIJI MICHIAKI
- Department of Obstetrics and Gynecology, Kurume University School of Medicine
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- KATO TOSHI
- Department of Obstetrics and Gynecology, Kurume University School of Medicine
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抄録
DMBA-induced adenocarcinomas were transplanted into the neonatal or young rats of the same strain (Wistar). Following subcutaneous injection, tumors exhibited two phases of growth: an inititial avascular phase characterized by slow growth, followed by a later phase of rapid growth in which the tumor became vascularized. The transplanted tumor was more hypervascular than the primary tumor. Histologically, the primary autochthonous tumors and the transplanted counterparts were similar. The most striking result of transplantation was a much more homogeneous solid pattern than occurred in the primary tumor. The second histologic finding was a reduced stromal reaction. Moreover, in the central area of the tumor, the relationship between the vasculature and cell proliferation was observed. The transplanted tumors may provide a useful experimental model for laboratory studies on the chemotherapy of ovarian cancer.
収録刊行物
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- The Kurume Medical Journal
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The Kurume Medical Journal 33 (2), 97-106, 1986
久留米大学医学部 The Kurume Medical Journal 編集部