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- KANO-TANAKA Kyoko
- Laboratory of Cell Biology, Aichi Cancer Center Research Institute Division of Neurobiology
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- FUKAMI Hiroko
- Laboratory of Cell Biology, Aichi Cancer Center Research Institute
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- KATO Taiji
- Department of Biochemistry, Nagoya City University Medical School
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- ITO Jin-ichi
- Department of Biochemistry, Nagoya City University Medical School
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- TANAKA Tatsuya
- Laboratory of Cell Biology, Aichi Cancer Center Research Institute Division of Neurobiology
抄録
The karyotypes of two malignant cell lines, GA1 and GA2, derived from chemically transformed glioblasts of WKA and BDIX rats, respectively, were investigated by G-banding at early passage numbers. In GA1, the karyotype 43; XY, 2q-, 4q+ and 12 trisomy, predominated and the cells with an additional 10p+ were less frequently observed. These consistent chromosomal changes were exactly identical with those previously found in virus-induced glioblast lines. GA2 had the normal male diploid stemline although a minor population of cells having the GA1-karyotype was also present. Thus, the present results combined with prior findings indicated that the in vitro transformed rat glial cells showed the common and specific changes in the karyotype regardless of the type of the oncogenic agent and rat strain.
収録刊行物
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- Proceedings of the Japan Academy. Ser. B: Physical and Biological Sciences
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Proceedings of the Japan Academy. Ser. B: Physical and Biological Sciences 62 (10), 395-397, 1986
日本学士院
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詳細情報 詳細情報について
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- CRID
- 1390282679124452736
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- NII論文ID
- 130000905799
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- ISSN
- 13492896
- 03862208
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可