内視鏡下鼻内手術におけるエピネフリン加コカイン麻酔の安全性と有効性

• 久保 伸夫

  関西医科大学耳鼻咽喉科学教室

• 中村 晶彦

  関西医科大学耳鼻咽喉科学教室

• 山下 敏夫

  関西医科大学耳鼻咽喉科学教室

書誌事項

タイトル別名

• EFFICACY AND COMPLICATIONS OF TOPICAL COCAINE ANESTHESIA IN FUNCTIONAL ENDOSCOPIC SINUS SURGERY

抄録

A 4% cocaine (total dose; 200mg) solution with 1mg epinephrine was used as a topical anesthetic for 178 cases undergoing functional endoscopic sinus surgery. Complications were investigated before and during surgery. Bleeding amount and operative duration were compared between patients with and without topical cocaine application. Tachycardia (26 cases) was the only complication encountered in this study. Tachycardia occurred at a high incidence in cases which used atropine as a premedication. Total bleeding amount did no differ significantly between those with and without topical cocaine. However, minimum bleeding cases (less than 20ml) were found in the cocaine group more frequently than in the non-cocaine group. Operative durations of cases with cocaine anesthesia were significantly shorter than cases without cocaine anesthesia. Those findings suggest that cocaine is effective for prevention of bleeding from micro-vessels and/or mucosal oozing, whereas bleeding from macro-vessels was not controlled by topical cocaine application. Topical cocaine anesthesia produced no major complications, even at 200mg, in the presence of 1mg epinephrine and when atropine use was avoided.

収録刊行物

• 日本耳鼻咽喉科学会会報

  日本耳鼻咽喉科学会会報 98 (8), 1263-1269,1361, 1995

  一般社団法人 日本耳鼻咽喉科頭頸部外科学会

キーワード

• コカイン麻酔
• 内視鏡下鼻内手術
• 副作用

詳細情報

• CRID: 1390282679988600448
• NII論文ID: 10006825009
• NII書誌ID: AN00191551
• DOI: 10.3950/jibiinkoka.98.1263
• ISSN: 18830854
• ISSN: 00306622
• PubMed: 7472763
• Web Site: https://search.jamas.or.jp/link/ui/1996080251
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可