胆道疾患時の胆のう胆汁内細菌に関する研究

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  • Anaerobic Bacteria in Biliary Diseases

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Although a considerable number of bacteriological investigation of bile has been carried out, very few used good anaerobic techniques. Clostridium welchii was noted to be the most common anaerobe in bile, and few reports have mentioned Bacteroides fragilis. Since B. fragilis is the most prevalent organism in intestinal flora and has frequently been isolated from the abscess of the liver, one can imagine that biliary tract is often infected by this anaerobe.<br>In this series, anaerobic and aerobic culture of the gallbladdlr bile was performed on the forty consecutive cases of biliaty tract surgery. Ten patients had sterile bile. Thirteen specimen yielded anaerobes as well as aerobes, and 17 yielded only aerobic bacteria. E. coli was the most common organism (25 strains), and B. fragilis (11 strains) was the most frequently encounted anaerobes, which, next to Klebsiella-Enterobacter (20 strains), stood third among all the isolates in this study. Cl. welchii was found in 6 bile specimen.<br>Frequent isolation of anaerobes, especially of B. fragilis, may be related to the anaerobic techniques used, and to background factors, for example, the age of the patients and high incidence of pigment stone.

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