書誌事項
- タイトル別名
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- ALKALINE PAOSPHATASE ISOENZYME FROM SPONTANEOUS COLON CARCINOMA OF HIGHLY INBRED RATS
抄録
The alkaline phosphatase (AP) isoenzyme from colonic carcinoma of the highly inbred Wistar-Furth (W-F) strain rat (carcinoma AP) was compared with AP from colonic mucosa of the same strain rat without colonic carcinoma (non-carcinoma AP), and also AP from normal rat colon of Wistar strain (normal AP) from which WF strain is derived.<br>The sepcific activity of carcinoma AP was ten-fold higher than that of normal AP, whereas that of non-carcinoma AP was almost the same as that of normal AP.<br>On polyacrylamide gel electrophoresis, carcinoma AP migrated as a slow-moving band, which was retarded by the treatment with neuraminidase.<br>Non-carcinoma AP and normal AP electrophoresed in three bands and two bands, respectively. Their electrophoretic mobilities were not affected by the treatment with neuraminidase. No significant differences between non-carcinoma AP and normal AP were found in other enzymatic properties. However, carcinoma AP was found to be completely different from APs of the other two sources.
収録刊行物
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- 日本消化器病学会雑誌
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日本消化器病学会雑誌 78 (6), 1209-1215, 1981
一般財団法人 日本消化器病学会