Ｂｏｗｅｎｏｉｄ　ｐａｐｕｌｏｓｉｓから有きょく細胞癌を発症した１症例

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  • A case which contracted squamous cell carcinoma from bowenoid papulosis.

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Bowenoid papulosis is clinically characterized by multiple, brown-black papules and plaques, occurring primarily on the genitalia of young adults, almost all under the age 40. The histologic appearance of Bowenoid papulosis is squamous cell carcinoma in situ similar to Bowen's disease. There is a broad consensus in the literature that Bowenoid papulosis is induced by human papilomavirus.<br>It has been documented that the lesions have a tendency toward spontaneous regression, however, the lesions herein reported developed into invasive squamous cell carcinoma.<br>The patient was a 27-year-old woman who had been Bowenoid papulosis on genitalia and bottock since she had been 13. The lesions had been treated by conservative therapy. The lesions developed invasive squamous cell carcinoma on buttock and therefore radical surgical therapy including rectal resection had to be done. We detected human papilomavirus-16 from both brown-black papules of Bowenoid papulosis and hyperkeratotic reddish tumor of squamous cell carcinoma in the method of polymerase chain reaction. We must notice Bowenoid papulosis can develope invasive squamous cell carcinoma.

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