Erythroid Crisis Caused by Parvovirus B19 Transmitted Via Red Blood Cell Transfusion

DOI Web Site 参考文献11件
  • Tsukada Yuiko
    Division of Hematology, Department of Internal Medicine, Keio University School of Medicine, Japan
  • Yokoyama Kenji
    Division of Hematology, Department of Internal Medicine, Keio University School of Medicine, Japan
  • Ishida Akaru
    Division of Internal Medicine, Tachikawa Hospital Federation of National Public Service Personnel Mutual Aid Associations, Japan
  • Handa Makoto
    Transfusion Medicine and Cell Therapy, Keio University School of Medicine, Japan
  • Mori Takehiko
    Division of Hematology, Department of Internal Medicine, Keio University School of Medicine, Japan
  • Kizaki Masahiro
    Department of Hematology, Saitama Medical Center, Saitama Medical University, Japan
  • Okamoto Shinichiro
    Division of Hematology, Department of Internal Medicine, Keio University School of Medicine, Japan

この論文をさがす

抄録

A 41-year-old man with hairy cell leukemia developed erythroid crisis after the transfusion of red cell concentrate. He was diagnosed with Parvovirus B19 infection based upon the presence of B19-specific IgM antibody and viral DNA in the sera. The repository sample from the corresponding red cell concentrate was negative for B19 antigen by red cell hemo-agglutination method, but was found to contain B19 virus DNA. Furthermore, a genomic PCR direct sequencing showed that B19 in both patient's sera and repository sample were identical. This is the first report directly demonstrating the transmission of B19 through B19 antigen-negative red cell concentrate transfusion. Further accumulation of the cases is warranted to estimate its incidence and to reconsider the screening methods of blood products.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 50 (20), 2379-2382, 2011

    一般社団法人 日本内科学会

参考文献 (11)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ