False-Positive Human Immunodeficiency Virus Antibody Test and Autoimmune Hemolytic Anemia in a Patient with Angioimmunoblastic T-Cell Lymphoma

  • Shida Seiji
    Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Japan
  • Takahashi Naoto
    Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Japan
  • Fujishima Naohito
    Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Japan
  • Kameoka Yoshihiro
    Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Japan
  • Nara Miho
    Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Japan
  • Fujishima Masumi
    Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Japan
  • Saitoh Hirobumi
    Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Japan
  • Tagawa Hiroyuki
    Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Japan
  • Hirokawa Makoto
    Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Japan
  • Ichinohasama Ryo
    Division of Hematopathology, Tohoku University Graduate School of Medicine, Japan
  • Sawada Kenichi
    Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Japan

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抄録

A 44-year-old woman was admitted with generalized lymphadenopathy, which was diagnosed as angioimmunoblastic T-cell lymphoma (AITL). The patient showed autoimmune hemolytic anemia (AIHA), polyclonal hypergammaglobulinemia and a high antinuclear antibody titer. Moreover, a human immunodeficiency virus (HIV)-1/2 screening test using the particle agglutination method was reactive. After chemotherapy for AITL, the AIHA was eliminated, and the false-positive HIV results were no longer detected. Autoimmunity associated with AITL is the likely cause of the cross-reaction with HIV and the AIHA. It is important to recognize that the cross-reaction with HIV can be a potential complication in AITL as well as AIHA.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 50 (20), 2383-2387, 2011

    一般社団法人 日本内科学会

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