A Case of Diabetic Ketoacidosis Associated with Guillain-Barre Syndrome

• Kanemasa Yusuke

  Center for Diabetes and Endocrinology, Tazuke Kofukai Medical Research Institute Kitano Hospital, Japan

• Hamamoto Yoshiyuki

  Center for Diabetes and Endocrinology, Tazuke Kofukai Medical Research Institute Kitano Hospital, Japan

• Iwasaki Yorihiro

  Center for Diabetes and Endocrinology, Tazuke Kofukai Medical Research Institute Kitano Hospital, Japan

• Kawasaki Yukiko

  Center for Diabetes and Endocrinology, Tazuke Kofukai Medical Research Institute Kitano Hospital, Japan

• Honjo Sachiko

  Center for Diabetes and Endocrinology, Tazuke Kofukai Medical Research Institute Kitano Hospital, Japan

• Ikeda Hiroki

  Center for Diabetes and Endocrinology, Tazuke Kofukai Medical Research Institute Kitano Hospital, Japan

• Wada Yoshiharu

  Center for Diabetes and Endocrinology, Tazuke Kofukai Medical Research Institute Kitano Hospital, Japan

• Koshiyama Hiroyuki

  Center for Diabetes and Endocrinology, Tazuke Kofukai Medical Research Institute Kitano Hospital, Japan

抄録

A 64-year-old woman was referred to our center presenting with thirst, malaise, and pain in both legs which occurred one week before admission. She was revealed to have hyperglycemia and diabetic ketoacidosis (DKA). After therapy for diabetic ketoacidosis was started, her blood glucose levels were improved, but urinary ketone body excretion persisted. Laboratory examination indicated a significant impairment of insulin secretion, although anti-GAD and anti-IA-2 antibody were not detected. After admission, she complained about weakness of lower extremities, which spread to her upper extremities. The diagnosis of Guillain-Barré syndrome (GBS) was made based on the nerve conduction study and cerebrospinal fluid analysis. The intravenous immunoglobulin therapy was started, and her muscle weakness showed gradual improvement. Although the possibility that GBS was casually accompanied with DKA could not be completely excluded, we considered that DKA triggered the development of GBS in this case. Although GBS is a rare condition, the present case suggests that GBS should be included in the differential diagnosis of DKA with its atypical course.<br>

収録刊行物

• Internal Medicine

  Internal Medicine 50 (19), 2201-2205, 2011

  一般社団法人 日本内科学会

キーワード

• diabetic ketoacidosis
• Guillain-Barré syndrome

詳細情報

• CRID: 1390282679846786176
• NII論文ID: 130001087904
• DOI: 10.2169/internalmedicine.50.5553
• ISSN: 13497235
• ISSN: 09182918
• Web Site: http://www.jstage.jst.go.jp/article/internalmedicine/50/19/50_19_2201/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2012227953
• 本文言語コード: en
• データソース種別:
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  • Crossref
  • CiNii Articles
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