Nutritional Assessment in Patients with Pulmonary Nontuberculous Mycobacteriosis
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- Ikegame Satoshi
- National Hospital Organization Omuta National Hospital, Japan
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- Maki Sanae
- National Hospital Organization Omuta National Hospital, Japan
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- Wakamatsu Kentaro
- National Hospital Organization Omuta National Hospital, Japan
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- Nagata Nobuhiko
- Department of Respiratory Medicine, Fukuoka University Chikushi Hospital, Japan
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- Kumazoe Hiroyuki
- National Hospital Organization Omuta National Hospital, Japan
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- Fujita Masaki
- Department of Respiratory Medicine, Faculty of Medicine, Fukuoka University, Japan
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- Nakanishi Yoichi
- Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University, Japan
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- Kawasaki Masayuki
- National Hospital Organization Omuta National Hospital, Japan
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- Kajiki Akira
- National Hospital Organization Omuta National Hospital, Japan
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抄録
Objective To determine the nutritional factors that influence disease spread in patients with pulmonary Mycobacterium avium complex (MAC) infection.<br> Methods A prospective observational study.<br> Patients Patients with pulmonary MAC infection were enrolled in this study. Chest computed tomography (CT), abdominal CT, and physical, clinical, and nutritional laboratory data were collected after obtaining informed consent.<br> Results Seventy-eight patients (16 males and 62 females) were consecutively enrolled. While the mean body mass index (BMI) was low (19.6 ± 2.7 kg/m2), the mean serum albumin concentration was within normal range (4.2 ± 0.2 g/dL). We evaluated the number of affected lung segments to define the degree of disease spread, and examined the relationships between various parameters and disease spread. Multivariate analysis identified the duration of the disease (+1.6 segment/100 months, p=0.03), BMI (-0.5 segment/BMI, p=0.003), and white blood cell count (+0.7 segment/1,000 WBC, p=0.03) as factors contributing to disease spread.<br> Conclusion BMI is an excellent marker for nutritional assessment and for predicting disease spread in patients with pulmonary MAC infection.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 50 (21), 2541-2546, 2011
一般社団法人 日本内科学会
