半導体TiO2微粒子配合歯磨剤の臨床応用 う蝕原性細菌との関連性

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タイトル別名
  • Clinical application of tooth paste containing semi-conductor TiO2 powder. Its relation to cariogenic bacteria.
  • Its Relation to Cariogenic Bacteria
  • 齲蝕原性細菌との関連性

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We examined changes in S. mutans, lactobacilli, total streptococci, and total anaerobic bacteria counts in plaque and saliva, when college student volunteers used toothpaste containing semiconductor TiO2, having bactericidal activity for S. mutans in vitro. S. mutans counts of plaque in subjects using toothpaste containing semiconductor TiO2 (TiO2 subjects) decreased and more significantly with time decreased than those of subjects using control paste (control subjects) after 2 weeks (p<0.01). Comparison of S. mutans counts between subjects using toothpaste contained TiO2 without semiconductor effect and control subjects were not significant. Lactobacilli counts of plaque in TiO2 subjects was also more sxgnificantly decreased than those in control subjects after 2 weeks (p<0.05). Salivary cariogenic bacterial counts were not changed by using toothpaste containing semiconductor TiO2.<BR>We suggest that toothpaste containg semiconductor TiO2 effective by to decreases S. mutans in plaque and contributes to the prevention of dental caries.

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