Application of hyperbaric oxygen therapy to osteoradionecrosis of the mandible.

• SANO Kazuo

  Second Department of Oral and Maxillofacial Surgery, Nagasaki University School of Dentistry

• YOSHIDA Shinichi

  Second Department of Oral and Maxillofacial Surgery, Nagasaki University School of Dentistry

• NINOMIYA Hidenori

  Second Department of Oral and Maxillofacial Surgery, Nagasaki University School of Dentistry

• SEKINE Joji

  Second Department of Oral and Maxillofacial Surgery, Nagasaki University School of Dentistry

• Pe Michael B.

  Second Department of Oral and Maxillofacial Surgery, Nagasaki University School of Dentistry

• INOKUCHI Tsugio

  Second Department of Oral and Maxillofacial Surgery, Nagasaki University School of Dentistry

• GOTO Shinichi

  Department of Anesthesiology, Nagasaki University School of Medicine

• SUMIKAWA Koji

  Department of Anesthesiology, Nagasaki University School of Medicine

Bibliographic Information

Other Title

• 下顎骨放射線骨壊死に対する高気圧酸素療法の応用

Abstract

Five cases of osteoradionecrosis (ORN) of the mandible were treated by hyperbaric oxygen therapy (HBO). In four cases, sequestrectomy in combination with HBO was performed. Furthermore, one of these cases underwent iliac bone grafting and HBO to correct mandibular discontinuity. One case underwent HBO after insertion of an implant into the irradiated mandible. Primary sites, with the histological diagnosis of the tumor and irradiation dose were: tonsil-squamous cell carcinoma (SCC), Linac X-ray 60 Gy; hard palatemalignant pleomorphic adenoma, Tele ⁶⁰ Co 50 Gy; floor of the mouth-SCC, Tele ⁶⁰ Co 38 Gy and ¹⁹⁸Au grain 98 Gy; tonsil-SCC, Tele ⁶⁰ Co 60 Gy; tongue-SCC, Linac X-ray 40 Gy. ORN appeared in these five cases 3 years, 24 years, 8 months, 1.5 years and 10 years after irradiation, respectively. HBO was performed under the condition of 2.8 ATA for 60 minutes and the patients were given pure oxygen (51/min) using a reservoir mask. All five cases were successfully treated. Otitis, one of the side effects of HBO, occurred in one case. It was managed by puncture of the tympanic membrane. As ORN is caused by hypoxia of the bone and surrounding tissues, HBO is considered to be one of the basic treatment methods for this condition.

Journal

• Japanese Journal of Oral and Maxillofacial Surgery

  Japanese Journal of Oral and Maxillofacial Surgery 40 (11), 1138-1145, 1994

  Japanese Society of Oral and Maxillofacial Surgeons

Keywords

• osteoradionecrosis
• mandible
• hyperbaric oxygen therapy
• iliac bone graft
• implant

Details

• CRID: 1390001206529548800
• NII Article ID: 130001349382
• DOI: 10.5794/jjoms.40.1138
• ISSN: 21861579
• ISSN: 00215163
• ISSN: http://id.crossref.org/issn/00215163
• Web Site: https://search.jamas.or.jp/link/ui/1995149581
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed