歯原性角化嚢胞に生じた下顎骨中心性癌の１症例

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  • A case of central carcinoma of the mandible arising in an odontogenic keratocyst.

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Carcinomas arising in the jaws are rare. The purpose of this report is to present a case of squamous cell carcinoma arising in an odontogenic keratocyst. A 72-year-old woman was referred to us for painful swelling of her left mandible with a small fistula of the surface mucosa. Radiographic examination showed an ill-defined lucent lesion in the left mandible. Segmental mandiblectomy and bilateral upper neck disection were performed based on a diagnosis of squamous cell carcinoma, determined from a biopsy specimen obtained at her former hospital. Histopathological examination of surgical specimens revealed squamous cell carcinoma as well as an odontogenic keratocyst. Furthermore, the transitional region from the cyst wall to carcinoma was clearly identified in serial sections.

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