唾液腺腫よう５２例の臨床的検討

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  • A clinical study of 52 salivary gland tumors.

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Fifty-two patients treated for salivary gland tumor in our hospital during the past 18 years from 1971 to 1989 were studied in this article.<BR>1. This study included 6 males and 11 females with benign and 15 males and 20 females with malignant, indicating that females have a higher frequency than males.<BR>2. Their mean age was 42.2 years old with benign and 53.2 with malignant, when the diagnosis were made.<BR>3. 17 cases of benign tumors were all plemorphic adenoma. Of malignant tumors, 12 were adenocystic carcinoma, 9 malignant pleomorphic adenoma, 8 mucoepidermoid tumor, 3 acinic cell tumor, 2 squamous cell carcinoma, and one undifferentiated carcinoma.<BR>4. These tumors arose in the major salivary glands in 17 patients (10 submandibular gland, 6 parotid gland, and 1 sublingual gland) and in minor salivary glands in 35 (21 palate, 8 buccal mucosa, 4 retromolar, 1 floor of the mouth, and 1 lip).<BR>5. Swelling was the most common symptom presented. Pain, ulcer, jaw trismus, and sensory nerve disturbance had a much greater frequency in cases of malignant tumors.<BR>6. Treatment result of previously untreated malignant epithelial tumors of the major and minor salivary gland were analysed with respect to stage, treatment modality and histology.<BR>(1) The 5-year cumulative survival rate was 93.8% in stages I and II and 40.5% in stages III and IV. The 10-year cumulative survival rate was 93.8% in stages I and II and 13.5% in stages III and IV.<BR>(2) The treatment modality which included surgery (S, S+C, S+C+R) had better prognosis than chemo and radiotherapy (C+R).<BR>(3) The 5-year and 10-year cumulative survival rates were found to be as follows: mucoepidermoid tumor 85.7% and 71.4%, respectively: adenoid cystic carcinoma both 78.6%: malignant pleomorphic adenoma 62.2% and 46.6% respectively.

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