悪性リンパ腫の臨床病理学的および免疫学的解析　　１０症例の検討（１９７６～１９８５）

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  • Clinico-pathological and immunophenotypic analysis of ten malignant lymphomas(1976-1985).

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Ten cases of malignant lymphoma examined clinically, histopathologically and immunophenotypically are reported.<BR>1) This study comprised of 8 males and 2 females patients; the majority advanced in age. Half were nodal lymphomas and half were extranodal.<BR>2) According to Ann Arbor staging classification, 3 cases were seen in each of Stages I, II and U. One case was excluded because it was a relapse. Histologically, all were non-Hodgkin's lymphomas comprising of small lymphocytic (1), mixed small and large cell (1), diffuse large cell (2), large cell, immunoblastic (4) and small non-cleaved cell (2), according to the Working Formulation. Six were of high grade malignancy.<BR>3) The immunophenotypic analysis for surface markers examined in 8 cases revealed that seven had characters of B-cells and only one had those of T-cells.<BR>4) Cases of Stage I or II were usually treated with irradiation in the past. But chemotherapy combined with radiotherapy has recently been put into practice even for most cases in these Stages.<BR>5) Only one patient is now surviving. The results clearly show that the prognosis of malignant lymphoma, especially in high grade, is extremely poor.

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