各種化学療法剤に対する　Ｒｉｃｋｅｔｔｓｉａ　ｐｒｏｗａｚｅｋｉｉ，　Ｒ．ｒｉｃｋｅｔｔｓｉｉ，　Ｒ．ｓｉｂｉｒｉｃａおよびＲ．ｔｓｕｔｓｕｇａｍｕｓｈｉの感受性の比較

• 宮村 定男

  新潟薬科大学微生物学教室

• 太田 達夫

  新潟薬科大学生物学教室

• 多村 憲

  新潟薬科大学微生物学教室

書誌事項

タイトル別名

• Comparison of in vitro susceptibilities of Rickettsia prowazekii, R. rickettsii, R. sibirica and R. tsutsugamushi to antimicrobial agents.
• カクシュ カガク リョウホウザイ ニ タイスル Rickettsia prow

抄録

The in vitro activities of 16 antimicrobial agents against Rickettsia prowazekii (Breinl strain), R. rickettsii (Bitterroot strain), R. sibirica (ATCC No.VR151) and R. tsutsugamushi (Gilliam, Karp, Kato, Shimokoshi, Kawasaki and Kuroki strains) were determined by the cell culture method. Tetracycline, demethylchlortetracycline, doxycycline, minocycline, chloramphenicol, kitasamycin and rifampicin were generally effective (MIC, 0.005-0.78μg/ml) to all strains tested. Quinolones such as norfloxacin, ciprofloxacin and ofloxacin were moderately active, but they were less active against R. tsutsugamushi than other rickettsial species. Penicillins and cephems showed low activity against most of the strains tested, but high concentrations of benzylpenicillin (MIC, 25-50μg/ml) inhibited R. prowazekii, R. rickettsii and R. sibirica. These findings may be applicable for differentiation of species of genus Rickettsia.

収録刊行物

• 日本細菌学雑誌

  日本細菌学雑誌 44 (5), 717-721, 1989

  日本細菌学会

キーワード

• General Medicine

詳細情報

• CRID: 1390282681427365888
• NII論文ID: 130001386354
• NII書誌ID: AN00189800
• DOI: 10.3412/jsb.44.717
• COI: 1:STN:280:By%2BD1c%2FitVM%3D
• ISSN: 18824110
• ISSN: 00214930
• NDL書誌ID: 3262599
• PubMed: 2512394
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I3262599
• Web Site: https://search.jamas.or.jp/link/ui/1991050971
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可