Malignant Pleural Effusion and Osteoblastic Metastases as the Initial Manifestation of Occult Gastric Cancer :

  • Shimizu Yuji
    Department of Respiratory Medicine, National Hospital Organization Takasaki General Medical Center
  • Kurosawa Koji
    Department of Medicine and Biological Science, Gunma University Graduate School of Medicine
  • Ueno Manabu
    Department of Medicine and Biological Science, Gunma University Graduate School of Medicine
  • Nakagawa Junichi
    Department of Medicine and Biological Science, Gunma University Graduate School of Medicine
  • Maeno Toshitaka
    Department of Medicine and Biological Science, Gunma University Graduate School of Medicine
  • Suga Tatsuo
    Department of Medicine and Biological Science, Gunma University Graduate School of Medicine
  • Motegi Mitsuru
    Department of Respiratory Medicine, National Hospital Organization Takasaki General Medical Center
  • Kanesawa Norio
    Department of Respiratory Medicine, National Hospital Organization Takasaki General Medical Center
  • Kurabayashi Masahiko
    Department of Medicine and Biological Science, Gunma University Graduate School of Medicine

書誌事項

タイトル別名
  • Malignant Pleural Effusion and Osteoblastic Metastases as the Initial Manifestation of Occult Gastric Cancer : A Case Report
  • A Case Report

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抄録

A 53-year-old man was admitted to our hospital because of lumbago. Gastrointestinal endoscopic examination performed on admission did not reveal any gross gastric abnormalities. Lumbar radiography and bone scintigraphy revealed multiple bone osteoblastic changes. Chest radiography showed right pleural effusion. The findings of the chest computed tomography and cytological examination of the pleural effusion were strongly suggestive of lung cancer. The patient was refractory to chemotherapy, and he died of cancer and disseminated intravascular coagulation. The autopsy revealed absence of primary lung cancer and the presence of tumor emboli in the right lung field. Swollen perigastric lymph nodes, tiny signet-ring cell carcinoma at the posterior wall of the stomach corpus, and severe vascular invasion were also observed at autopsy.<BR> Therefore, signet ring cell carcinoma of the stomach should be considered as a possible diagnosis in early-stage gastric cancer patients who develop osteoblastic metastasis and pleural effusion.

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