ニフェジピン服用患者の歯肉所見

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タイトル別名
  • Clinical and histopathological observation of the gingivae in heart patients treated with nifedipine - A report of three cases.
  • A Report of Three Cases

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Gingival examination in three patients treated with nifedipine, a new agent belonging to the calcium antagonist group of drugs in cardiology, were performed.<br>In one patient administered nifedipine 44mg/day for about 6 months, severe gingival hyperplasia was observed. Gingival tissues were firm and fairly hard to touch and lesions appeared to originate from the interdental papillae. Gingival biopsy revealed pronounced fibrosis with fibroblastic proliferation within the lamina propria. Hyperplastic changes in gingiva were similar clinically and histopathologically to the hyperplasia caused by diphenylhydantoin (Dilantin).<br>In other two cases, gingival appearances were clinically normal. However, accumulation of connective tissue substance within the propria and epitherial acanthosis were advanced in the histopathological examination of gingival biopsies.

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詳細情報 詳細情報について

  • CRID
    1390001204413547008
  • NII論文ID
    130001474491
  • DOI
    10.2329/perio.27.224
  • COI
    1:STN:280:DyaL2M3ptFWlsg%3D%3D
  • ISSN
    1880408X
    03850110
    http://id.crossref.org/issn/03850110
  • PubMed
    3861738
  • Web Site
    https://search.jamas.or.jp/link/ui/1986020290
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • Crossref
    • PubMed
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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