モロニー肉腫ウイルス誘発骨腫の組織化学的所見

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  • Histochemical Studies on Molony Sarcoma Virus-Induced Osteosarcoma in Rats

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For induction of experimental bone tumor, newborn Wistar-King-Aptekman or wistar-Lewis rats were received the intraperitoneal injection of the virus suspension.<br>The samples from the induced bone tumors were examined by histochemical procedures on mucopolysaccharides, nucleic acid, lipid, non-specific alkaline phosphatase and acid phosphatase. The tumor cytoplasm showed the intensive activity of alkaline phosphatase. Lipid contents and glycogen were scanty.<br>The histochemical findings of the induced tumor in rats were almost similar to that of osteoblastic type of human osteosarcoma.

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