A case of double cancer with epithelial-myoepithelial carcinoma in the submandibular gland and lung cancer

  • Sakurai Hiromasa
    Department of Dentistry, Oral and Maxillofacial・Plastic and Reconstrauctive Surgery, Faculty of Medicine, Yamagata University
  • Yoshida Takafumi
    Depertment of Dentistry and Oral Surgery Nihonkai General Hospital Yamagata Prefectural and Sakata Municipal Hospital Organaization
  • Ozaki Masashi
    Department of Dentistry, Oral and Maxillofacial・Plastic and Reconstrauctive Surgery, Faculty of Medicine, Yamagata University
  • Hamamoto Yoshioki
    Depertment of Dentistry, Oral and Maxillofacial Surgery, Yamagata Prefectural Central Hospital
  • Iino Mitsuyoshi
    Department of Dentistry, Oral and Maxillofacial・Plastic and Reconstrauctive Surgery, Faculty of Medicine, Yamagata University
  • Kobayashi Takanori
    Division of Oral Pathology, Niigata University Graduate School of Medical and Dental Sciences
  • Saku Takashi
    Division of Oral Pathology, Niigata University Graduate School of Medical and Dental Sciences

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Other Title
  • 顎下腺に生じた上皮筋上皮癌と肺癌の重複癌の1例

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Abstract

Epithelial-myoepithelial carcinoma (EMC) is a rare malignant salivary gland neoplasm accounting for approximately 1% of all salivary gland tumors. EMC is typically found in the parotid gland. In this report, we present a case of double cancer with EMC in the submandibular gland and lung cancer.<br>The patient was a 57-year-old woman. She had been aware of a left submandibular mass for ten years. An elastic and hard thumb-sized mass in the submandibular region was palpated. CT examination revealed neoplastic lesions in the left submandibular gland and the left upper lung. In April 2008, based on the diagnosis of tumor of the left submandibular gland and metastatic lung cancer in the left upper lobe, excision of the submandibular gland tumor was performed. Subsequently, a left superior lobectomy was performed in the Department of Thoracic Surgery in our hospital in May 2008. Postoperative microscopic examination revealed that the submandibular tumor was characterized by a bilayer structure composed of outer clear myoepithelial cells and inner ductal cells. The pathological diagnosis was EMC. The lung tumor was diagnosed as bronchioloalveolar carcinoma, and the two lesions were independent of each other.<br>The postoperative course was uneventful. The patient has been well and free from the disease for 3 years postoperatively.

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