近赤外光を用いる無侵襲生体計測

• 田村 正秀

  旭川医科大学第一外科

• 高木 勇

  旭川医科大学第一外科

• 橘秀 光

  旭川医科大学第一外科

• 久保 良彦

  旭川医科大学第一外科

• 鮫島 夏樹

  旭川医科大学第一外科

書誌事項

タイトル別名

• Non-invasive analysis of tissue oxygen metabolism by near infrared spectrophotometry.

抄録

Brain oxygen metabolism was noninvasively studied by the simultaneous measurement of hemoglobin (Hb) oxygenation and cytochrome oxidase (Cyt. aa₃) redox state in the rat brain using near infrared transmission spectrophotometer. Our estimation of the oxygenation level of brain Hb revealed that present optical measurement picked up mainly that of venous blood. Sharp reduction of the oxidase occured at the oxygen concentration below 15% in the inspired gas, which indicated the slow down of the mitochondrial respiration. Application of our techniques for the studies of brain metabolism in acute hemorrhagic shock, and during pentylenetetrazol seizures in the rat were also presented. Effects of hyperventilation on brain oxygen metabolism were successfully studied in human volunteers by the reflectance spectrophotometry.

収録刊行物

• 人工臓器

  人工臓器 16 (3), 1576-1579, 1987

  一般社団法人 日本人工臓器学会

キーワード

• near infrared spectorophbtometry
• brain oxygen metabolism
• Hb-oxygenation
• Cyt. oxidase (aa₃) redox
• blood volume

詳細情報

• CRID: 1390282679934673152
• NII論文ID: 130001735004
• DOI: 10.11392/jsao1972.16.1576
• ISSN: 18836097
• ISSN: 03000818
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可