Ｃｅｌｌｕｌｏｓｅ　ｔｒｉａｃｅｔａｔｅ中空糸膜を用いた血しょう分離器の基礎的臨床的検討

DOI

書誌事項

タイトル別名
  • Fundamental and clinical evaluation of a new cellulose triacetate hollow fiber membrane plasma separator.

抄録

Evaluation is made of a fundamental and clinical study the newly developed hollow fiber plasma separator, Plasma Star (PM50). The Plasma Star hollow fiber consists of cellulose triacetate and has wall thickness of 80μm, an internal diameter of 270μm, and a maximum pore size of 0.4μm. Its effective surface area is 0.5m2. In the fundamental study, transmembrane pressures were stable at 8-13mmHg throughout the perfusion, during which the blood and plasma flow was 100ml/min and 35-38ml/min, respectively. Sieving coefficients of T. P., albumin, gamma-globulin and beta-globulin were 0.95 in each case. In the clinical study, eleven patients were treated 32 times for over 2 hours. The sieving coefficients of albumin, IgG, IgA, and IgM were 91%, 91%, 94%, and 98%, respectively. Mean decrease in leukocyte and platelets during plasma exchange were 4% and 10%. Red blood cell counts remained at the same level. There were no differences on the data of blood chemistry between before and after plasma exchange.

収録刊行物

  • 人工臓器

    人工臓器 15 (3), 1633-1636, 1986

    一般社団法人 日本人工臓器学会

キーワード

詳細情報 詳細情報について

  • CRID
    1390001204959106560
  • NII論文ID
    130001735578
  • DOI
    10.11392/jsao1972.15.1633
  • ISSN
    18836097
    03000818
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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