Biocompatibility of dialyser - Biological action of cellulose acetate membrane extracts.

• KINUGASA E.

  Fujigaoka Hospital, Showa University

• SEKIGUCHI T.

  Fujigaoka Hospital, Showa University

• AKIZAWA T.

  Fujigaoka Hospital, Showa University

• KITAOKA T.

  Fujigaoka Hospital, Showa University

• KOSHIKAWA S.

  Fujigaoka Hospital, Showa University

• NAKABAYASHI N.

  東京医科歯科大学医用器材研究所

• YAMAMOTO M.

  繊維高分子材料研究所

• URYU T.

  東京大学生産技術研究所

Bibliographic Information

Other Title

• 血液透析器の生体適合性　　セルロース素材抽出物の作用について
• Biological action of cellulose acetate membrane extracts
• ―セルロース素材抽出物の作用について―

Abstract

We evaluated biological action of extracts from partially acetylated cellulose acetate, which originated from wood pulp. This material caused severe hyperemia in iris and sclera soon after injection in rabbits. In mongrel dogs, cough, sneezing and tachypnea in addition to hyperemia in sclera were followed immediately after injection of the material. In the latter experiments, it was noted severe transient leukopenia and thrombocytopenia within ten minutes after injection. Severe transient hypoxia occured in one experiment, which showed most profound leukopenia and respiratory symptoms. The structure of this biologically active material was identified as partially acetylated glucan and/or xylan by ¹³CNMR analysis.

Journal

• Jinko Zoki

  Jinko Zoki 15 (1), 248-251, 1986

  JAPANESE SOCIETY FOR ARTIFICIAL ORGANS

Keywords

• Cellulose acetate
• Wood pulp
• Iritis
• Glucan
• Xylan

Details

• CRID: 1390282679934478720
• NII Article ID: 130001735684
• DOI: 10.11392/jsao1972.15.248
• ISSN: 18836097
• ISSN: 03000818
• Text Lang: ja
• Data Source:
  • JaLC
  • CiNii Articles
• Abstract License Flag: Disallowed