高圧蒸気滅菌ダイアライザーの生体適合性

• 坂下 恵一郎

  増子病院

• 筒井 敏彦

  増子病院

• 利見 秀雄

  増子病院

• 伊藤 晃

  増子病院

• 山崎 親雄

  増子病院

• 増子 和郎

  増子病院

書誌事項

タイトル別名

• A biocompatibility of the dialyzer sterilized with steam autoclaving.

抄録

We compared each other two types (dry and wet) of AC dialyzer in basic experiment and clinical study. The dry type showed high value of ΔKMnO₄, residue on evaporation and UV spectrum as well. Hemolysis test was positive only in solution filled up in the wet type. LT of the dialyzer revealed different results when LT was done with three reagents for various samples. There is hardly possibility that LAL-RM arising from non-used dialyzer is endtoxin. Both dry and wet types showed same movements as to change in the leucocyte and complement during hemodialysis. Amoung patients of using AC dialyzer for long term, the dry type group exhibited significant high value in LT by Pyrosate and Toxicolor Test. All cases were negative by Pyrogen. There is also rare in possibility that LAL-RM detected by two reagents mentioned above is endtoxin. No significant difference between clinical data of dry type group and that of wet except IgE was found. We, however, think to require further examination about clinical study of AC dialyzer.

収録刊行物

• 人工臓器

  人工臓器 14 (1), 26-29, 1985

  一般社団法人 日本人工臓器学会

キーワード

• biocompatility
• autoclave dialyzer
• dry and wet type
• endtoxin
• LAL-RM

詳細情報

• CRID: 1390001204955288960
• NII論文ID: 130001736194
• DOI: 10.11392/jsao1972.14.26
• ISSN: 18836097
• ISSN: 03000818
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可