Ceftriaxoneと他cephem系抗生物質との抗菌力の比較検討
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- 岩沢 武彦
- 初富クリニック耳鼻咽喉科
書誌事項
- タイトル別名
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- Comparison of antibacterial activities of ceftriaxone and other cephems.
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A new cephem antibiotic, Ceftriaxone (CTRX) was compared with other cephems as to in vitro antibacterial activities. CTRX revealed an excellent, broad spectrum antibacterial activity against gram-positive and gram-negative bacteria, as well as an antibacterial efficacy, similarly to Cefotaxime which was used as a reference drug.<br>The MIC of CTRX against S. aureus isolated from otorrhoea was distributed at a range from 0.78 to 25 μg/ml, showing a peak at 3.13 μg/ml. P. mirabilis, E. coli and K. pneumoniae were inhibited by ≤0.2 to 0.39 μg/ml of CTRX. It's activity was similar to that of Cefotaxime, Cefotiam, Cefoperazone, Ceftizoxime, Cefotetan, Latamoxef, Cefmenoxime and superior to that of Cefazolin, Cephapirin, Ceftezole and Cephacetrile against various pathogenic gram-negative bacteria.<br>CTRX showed MICs of 3.13 to 12.5 μg/ml, its peak being 12.5 μg/ml against 60 strains of pathogenic P. aeruginosa.
収録刊行物
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- 耳鼻咽喉科臨床
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耳鼻咽喉科臨床 79 (10), 1719-1728, 1986
耳鼻咽喉科臨床学会
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詳細情報 詳細情報について
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- CRID
- 1390282679239689216
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- NII論文ID
- 130001810015
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- ISSN
- 18844545
- 00326313
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可