Multicentric carcinoma in the oral cavity and pharynx; A report of eight cases.

DOI 2 Citations

Bibliographic Information

Other Title
  • 口腔・咽頭多発癌の８例
  • A Report of Eight Cases

Search this article

Abstract

We studied the clinical charactristics of multicentric carcinoma in the oral cavity and pharynx. During a period of 12 years from 1977 to 1988 at Shikoku Cancer Center Hospital, 8 out of 332 patients (2.4%) with squamous cell carcinoma of the oral region (oral cavity and oropharynx) had multicentric carcinomas. In 5 patients the cancers developed synchronously and in 3 at different times.<br>Smoking and alcohol drinking were considered to be significant factors related to the carcinogenesis of multicentric carcinoma, although the concept of field carcinogenesis advocated by Slaughter was also considered.<br>However, we could not rule out the role of radiation in the patients who had had radiotherapy and then developed nonsynchronous multicentric cancer.<br>For patients in the high risk group because of a history of smoking and drinking, initial multimodal therapy and long term following-up should be emphasized to improve the clinical outcome.

Journal

Citations (2)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top