Synthesis of Marine Diterpene Isocyanide (-)-Kalihinol Y and Diterpene Isothiocyanate (-)-10-Epi-kalihinol I

  • Miyaoka Hiroaki
    School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
  • Abe Yasunori
    School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
  • Kawashima Etsuko
    School of Pharmacy, Tokyo University of Pharmacy and Life Sciences

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  • Synthesis of Marine Diterpene Isocyanide (−)-Kalihinol Y and Diterpene Isothiocyanate (−)-10-Epi-kalihinol I

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The authors described the first synthesis of diterpene isocyanide (−)-kalihinol Y and diterpene isothiocyanate (−)-10-epi-kalihinol I from synthetic intermediates of kalihinol A. The absolute structures of these compounds were confirmed by these syntheses.

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