Rates of Coronary Intervention Due to De Novo Significant Atherosclerosis and Cardiac Death Are Very Low in Korean Patients With Vasospastic Angina
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- Shin Dong Il
- Division of Cardiology, Department of Internal Medicine, Incheon St. Mary’s Hospital The Catholic University of Korea Division of Cardiology, Department of Internal Medicine, Incheon St. Mary’s Hospital The Catholic University of Korea
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- Baek Sang Hong
- Seoul St. Mary’s Hospital The Catholic University of Korea Seoul St. Mary’s Hospital The Catholic University of Korea
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- Seo Suk Min
- Division of Cardiology, Department of Internal Medicine, Incheon St. Mary’s Hospital The Catholic University of Korea Division of Cardiology, Department of Internal Medicine, Incheon St. Mary’s Hospital The Catholic University of Korea
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- Koh Yoon-Seok
- Uijeongbu St. Mary’s Hospital, Uijeongbu The Catholic University of Korea Uijeongbu St. Mary’s Hospital The Catholic University of Korea
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- Choi Yoon Seok
- Yeouido St. Mary’s Hospital The Catholic University of Korea Yeouido St. Mary’s Hospital The Catholic University of Korea
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- Kim Dong Bin
- St. Paul’s Hospital The Catholic University of Korea St. Paul’s Hospital The Catholic University of Korea
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- Her Sung Ho
- Daejeon St. Mary’s Hospital The Catholic University of Korea Daejeon St. Mary’s Hospital The Catholic University of Korea
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- Kim Pum-Joon
- Seoul St. Mary’s Hospital The Catholic University of Korea Seoul St. Mary’s Hospital The Catholic University of Korea
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- Lee Jong Min
- Uijeongbu St. Mary’s Hospital, Uijeongbu The Catholic University of Korea Uijeongbu St. Mary’s Hospital The Catholic University of Korea
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- Kim Hee Yeol
- Bucheon St. Mary’s Hospital The Catholic University of Korea Bucheon St. Mary’s Hospital The Catholic University of Korea
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- Yoo Ki Dong
- St. Vincent’s Hospital The Catholic University of Korea St. Vincent’s Hospital The Catholic University of Korea
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- Seung Ki-Bae
- Seoul St. Mary’s Hospital The Catholic University of Korea Seoul St. Mary’s Hospital The Catholic University of Korea
書誌事項
- タイトル別名
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- – 36-Month Follow-up Results of the Vasospastic Angina in the Catholic Medical Center (VA-CMC) Registry –
抄録
Background: The rate of percutaneous coronary intervention (PCI) due to the development of significant atherosclerosis and the cardiac mortality rate in Korean patients with vasospastic angina (VSA) was estimated. Methods and Results: A total of 831 patients with VSA from 8 centers were registered in the Vasospastic Angina in the Catholic Medical Center (VA-CMC) registry. Their provocation tests for VSA showed positive results. The patients with significant atherosclerosis (>50% luminal narrowing) on the baseline angiography were excluded. Subjects were VSA patients without significant atherosclerosis. A total of 745 patients were included in the final analysis. The mean follow-up duration was 36.1±9.8 months. The PCI rate was 2.01% (15/745). Current smoking (odds ratio: 2.31, P<0.05) and high levels of baseline high-sensitivity C-reactive protein (hsCRP) (odds ratio: 1.57, P<0.05) were independent risk factors for PCI. The mortality rate was 2.55% (19/745). Eleven patients died of cardiac causes (1.48%). Cessation of medication was an independent risk factor for cardiac mortality (odds ratio: 1.47, P<0.05). The mean duration from the diagnosis to the cardiac deaths was 10.6±4.3 months. Conclusions: Korean patients with VSA demonstrated low rates of development of significant atherosclerosis leading to PCI and cardiac mortality. However, cessation of medication, smoking, and high baseline hsCRP were the independent risk factors for unfavorable outcomes. (Circ J 2012; 76: 2681–2689)<br>
収録刊行物
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- Circulation Journal
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Circulation Journal 76 (11), 2681-2689, 2012
一般社団法人 日本循環器学会