Volumetric and Functional Assessment of Ventricles in Pulmonary Hypertension on 3-Dimensional Echocardiography

• Inaba Toshiro

  Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo

• Yao Atsushi

  Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo

• Nakao Tomoko

  Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo

• Hatano Masaru

  Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo

• Maki Hisataka

  Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo

• Imamura Teruhiko

  Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo

• Shiga Taro

  Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo

• Yamazaki Tadashi

  Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo

• Sonoda Makoto

  Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo

• Kinugawa Koichiro

  Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo

• Shiota Takahiro

  Cedars-Sinai Medical Center and David Geffen School of Medicine at UCLA

• Suzuki Junichi

  Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo

• Takenaka Katsu

  Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo

• Hirata Yasunobu

  Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo

• Nagai Ryozo

  Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo

抄録

Background: Non-invasive assessment of volume and function on the right ventricle (RV) for pulmonary hypertension (PH) is limited. Methods and Results: Patients with PH (n=23) underwent 3-dimensional (D) echocardiography (3DECHO), with cardiac magnetic resonance imaging to confirm its precision, and right heart catheterization. On linear regression analysis the RV end-systolic volume index (ESVI) was positively correlated with pulmonary vascular resistance (PVR) and mean pulmonary arterial pressure (mPAP; R=0.42 and 0.46, P=0.03 and 0.03, respectively). The RV end-diastolic volume index (EDVI) was positively correlated with mPAP (R=0.41, P<0.05). The left ventricular (LV) EDVI was inversely correlated with PVR (R=−0.48, P=0.02). The RV ejection fraction was inversely correlated with PVR and mean right atrial pressure (mRAP; R=−0.57, and −0.45, P=0.004, and 0.03, respectively). RVEDVI/LVEDVI and RVESVI/LVESVI (the diastolic and systolic remodeling indices, respectively) had a significantly positive linear relationship with PVR (R=0.67 and 0.55, P=0.0005 and 0.006, respectively), and the former had a significantly positive linear relationship with mRAP (R=0.42, P<0.05). During the recovery process in 1 specific case, the remodeling indices maintained a significant linear relationship with the hemodynamic parameters. Conclusions: Novel indices provided by 3DECHO may be utilized as alternative indicators of hemodynamic changes in PH patients.  (Circ J 2013; 77: 198–206)<br>

収録刊行物

• Circulation Journal

  Circulation Journal 77 (1), 198-206, 2013

  一般社団法人 日本循環器学会

キーワード

• 3-D echocardiography
• Magnetic resonance imaging
• Pulmonary hypertension
• Pulmonary vascular resistance
• Remodeling index

詳細情報

• CRID: 1390282680080655360
• NII論文ID: 10031131587
• NII書誌ID: AA11591968
• DOI: 10.1253/circj.cj-12-0203
• COI: 1:STN:280:DC%2BC3s%2FgslygsQ%3D%3D
• ISSN: 13474820
• ISSN: 13469843
• PubMed: 23018765
• Web Site: https://www.jstage.jst.go.jp/article/circj/77/1/77_CJ-12-0203/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2013357880
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可