Aortic Atherosclerotic Plaque and Long-Term Prognosis in Patients With Atrial Fibrillation
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- Okura Hiroyuki
- Division of Cardiology, Bell Land General Hospital
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- Kataoka Toru
- Division of Cardiology, Bell Land General Hospital
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- Yoshiyama Minoru
- Department of Internal Medicine and Cardiology, Osaka City University Graduate School of Medicine
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- Yoshikawa Junichi
- Division of Cardiology, Nishinomiya Watanabe Cardiovascular Center
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- Yoshida Kiyoshi
- Division of Cardiology, Kawasaki Medical School
書誌事項
- タイトル別名
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- – A Transesophageal Echocardiography Study –
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Background: Both left atrial spontaneous echo contrast (LASEC) and aortic atherosclerotic plaque (AoP) ≥4.0mm in thickness are predictors of cardiovascular events after stroke. The aim of this study was to investigate impact of AoP ≥4.0mm or LASEC on cardiovascular events in patients with atrial fibrillation (AF). Methods and Results: One hundred and eight consecutive patients with AF were enrolled and studied. Patients were grouped according to the presence or absence of AoP ≥4.0mm in the proximal aortic arch on transesophageal echocardiography (TEE). Cardiovascular events included death, myocardial infarction, ischemic stroke, systemic embolism and congestive heart failure. During a follow-up period (median, 3.9 years), cardiovascular event-free survival rate was significantly lower in patients with AoP ≥4.0mm than in patients without AoP ≥4.0mm (log-rank, P=0.01). In contrast, patients with LASEC showed a trend toward lower cardiovascular event-free survival than those without LASEC (log-rank, P=0.10). Univariate TEE predictors of cardiovascular events were AoP ≥4.0mm, LASEC and left atrial appendage flow velocity. On multivariate Cox regression analysis, AoP ≥4.0mm was the only TEE predictor of cardiovascular events during follow-up (P=0.02, hazard ratio, 2.6; 95% confidence interval: 1.1–6.0). Conclusions: In the present unselected patients with AF, AoP predicted long-term cardiovascular events. (Circ J 2013; 77: 68–72)<br>
収録刊行物
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- Circulation Journal
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Circulation Journal 77 (1), 68-72, 2013
一般社団法人 日本循環器学会
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詳細情報
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- CRID
- 1390282680080562048
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- NII論文ID
- 10031131569
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- NII書誌ID
- AA11591968
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- ISSN
- 13474820
- 13469843
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- PubMed
- 23047295
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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